TABLE 5.
ICS Doses | Person-Years at Risk | Total (n = 494) (%) | Unadjusted HR (95% CI) | Adjusted HR* (95% CI) |
---|---|---|---|---|
Continuous variable (per 100 μg/d) | 762 | 494 | 1.06 (1.02–1.11) | 1.04 (0.99–1.09) |
Categorical variable | ||||
Nonusers | 752 | 479 | Referent | Referent |
< 1,200 μg/d | 11 | 12 | 1.99 (1.02–3.88) | 1.25 (0.63–2.47) |
⩾ 1,200 μg/d | 0.15 | 3 | 6.38 (1.57–25.19) | 4.67 (1.06–20.53) |
For definition of abbreviations, see Table 4.
Adjusted for age, smoking status and smoking intensity, history of malignancy other than skin cancer, Seattle Index of Comorbidity score, and bronchodilator use.