TABLE 3.
ASSOCIATIONS BETWEEN OCCUPATIONAL EXPOSURES AND ASTHMA AMONG TEXAS HEALTH CARE WORKERS: FINAL MULTIVARIABLE LOGISTIC REGRESSION MODELS*
| Odds Ratio (95% CI)†
|
|||
|---|---|---|---|
| Occupational Exposure | n (%) | Reported Asthma‡ | BHR-related Symptoms§ |
| Cleaning agents | |||
| Used in patient care | 2,705 (98.8) | 1.60 (0.18–14.16) | 0.79 (0.35–1.78) |
| Instrument cleaning | 1,257 (45.9) | 2.22 (1.34–3.67) | 1.26 (0.95–1.67) |
| Surface cleaners | 1,943 (71.0) | 2.02 (1.20–3.40) | 1.63 (1.21–2.19) |
| Latex | |||
| Pre-1992 | 1,907 (69.7) | 2.04 (0.87–4.75) | 1.04 (0.72–1.51) |
| 1992–2000 | 1,556 (56.8) | 2.17 (1.27–3.73) | 1.26 (0.93–1.72) |
| After 2000 | 88 (3.2) | 0.42 (0.13–1.29) | 0.61 (0.34–1.11) |
| Aerosolized medications | 1,255 (45.8) | 1.72 (1.05–2.83) | 1.40 (1.06–1.84) |
| Adhesives/solvents/gases | |||
| Used in patient care | 1,921 (70.2) | 1.68 (0.99–2.86) | 1.65 (1.22–2.24) |
| On surfaces | 581 (21.2) | 0.59 (0.26–1.33) | 0.98 (0.64–1.51) |
| Miscellaneous | 869 (31.7) | 0.53 (0.32–0.88) | 0.78 (0.60–1.01) |
| Spill at work | 163 (6.0) | 1.23 (0.53–2.87) | 2.02 (1.28–3.21) |
Definition of abbreviations: BHR = bronchial hyperresponsiveness; CI = confidence interval.
Total n = 2,738 in the analytic sample. Values shown in boldface are statistically significant.
Adjusted for seniority (quartiles), race/ethnicity, body mass index, and atopy; weighted survey samples.
Goodness-of-fit, assessed through F-adjusted mean residual test for sample survey data, p > 0.05 for all models. Reference category for all exposure variables is the absence of such exposure.
Self-reported history of physician-diagnosed asthma, with onset after entry into the health care profession.
Eight-item predictor for BHR, PC20 ⩽ 4 mg/ml.