Skip to main content
. 2006 Dec 29;36(5):552–561. doi: 10.1165/rcmb.2006-0320OC

Figure 5.

Figure 5.

CTGF inhibits branching morphogenesis in E12.5 mouse embryonic lung explants. E12.5 lung explants were treated with CTGF (5–250 ng/ml) for 48 h and photomicrographs were taken under the same magnification at 48 h. (A) Control lung explant; lung explants treated with CTGF 5 ng/ml (B), 50 ng/ml (C), and 250 ng/ml (D). (E) Graphical representation of the quantification of terminal branching after culture for 48 h. Each bar represents mean ± SD from six lung explants. CTGF dose-dependently inhibited branching morphogenesis. *P < 0.001 compared with control.