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Reduced quasi-static pulmonary compliance in Pearl mice after bleomycin challenge. Mice were challenged with intratracheal bleomycin (0.025 U) or an equal volume of sterile saline as a control. After 7 d, tracheostomized mice underwent physiologic testing with the Scireq flexivent system (n = 4 per group, *P < 0.05 for WT versus Pearl bleomycin and #P < 0.01 for Pearl control versus Pearl bleomycin). Open bars, wild type; solid bars, Pearl.
