The PTS and the proposed Mif pathways. CM, cytoplasmic membrane; l-di-GMP, linear di-GMP; EIIC and EIIB, subunits of the glucose-specific PTS transporter; EIIA, HPr, and EI, signaling components of the PTS pathway; Pyr, pyruvate. Dotted lines represent a pathway known to function in E. coli. See the text for the proposed interaction between the PTS and Mif pathways (a through d) and their effects upon flagellar biogenesis and on bioluminescence.