Table 1.

Systems and protocols used by institutions in multi-center study (Testing Data)

	Institution 1	Institution 2	Institution 3	Institution 4	Institution 5
MRI System	Siemens Sonata	Philips Intera	Siemens Magnetom	GE LX	GE Signa
Sequence	Spoiled gradient-echo	Gradient echo with Sense software	Gradient echo	FSPGR	FSPGR
Bilateral/Unilateral	Bilateral Interleaved	Unilateral	Unilateral	Unilateral and Bilateral Sequential	Bilateral affected breast first and bilateral contralateral breast first
Saline push after injection of gad?	Yes	No: 8 C/3 NC. Yes: 16C/1 NC	Yes	Yes	Yes
Matrix	256x256 and 512x512	179x256	256x256	256x292	256x256
cancerous (C) breasts	5	24	4	28	10
non-cancerous (NC) breasts	43	4	8	43	10
Basis of assessment of non-cancerous	No suspicious findings on MRI, ultrasound or mammo, no FU.	Biopsy of most suspicious lesion, No FU info available.	Mastectomy (3); Mammography with 6–14 mo. follow-up (5).	Imaging follow up min 6 mo. (29); no suspicious finding on MRI, no FU (14).	Biopsy of most suspicious lesion, No FU info available.
Data from DICOM headers: Minimum-Maximum (Mean)
Interval between time of pre-contrast and time of post-contrast image used in study (sec)	115–317 (220)	157–534 (318)	241–904 (588)	170–784 (374)	373–1713 (943)
Echo time (msec)	1.8 – 6.5 (4.5)	5.9 – 6.5 (6.3)	4.5 – 4.5 (4.5)	2.3 – 5.0 (2.8)	1.8 – 2.4 (2.1)
Repetition time (msec)	7.7 – 26.0 (11.8)	32.9 – 33.0 (32.9)	11 – 20.0 (11.8)	17.0 – 20.0 (17.6)	17.0 – 24.6 (17.8)
Flip angle (deg)	25 – 30 (35.4)	55 – 55 (55.0)	35 – 40 (35.4)	35 – 45 (37.0)	35 – 35 (35.0)
Slice Thickness (mm)	2.2 – 4.2 (2.9)	3.0 – 4.4 (3.9) with 2 mm overlap	2.2 – 3.0 (2.9)	1.0 – 4.0 (3.0)	2.0 – 3.0 (2.9)
FOV (mm)	18 – 22 (20.0)	20 – 22 (20.2)	20 – 20 (20.0)	18 – 24 (20.3)	18 – 22 (19.6)