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. 2007 Jul 1;21(13):1615–1620. doi: 10.1101/gad.1534807

Figure 1.

Figure 1.

Aberrant DTC migration in vab-3 mutants. (A) DTCs (blue crescents) originate on the ventral surface of the nematode body (dashed line) on the distal edges of the gonad primordium in L1. In L2, they migrate away from the center along the ventral surface, then turn to the dorsal side during L3. A second turn redirects migration along the dorsal surface toward the center of the nematode during L4. Migration then terminates dorsal to the vulva, producing the adult gonad. The developmental stage is indicated at right of each diagram. DIC image of adult wild-type N2 gonad arm (B), adult vab-3(mw105) gonad arm with multiple dorsal turns (C), and vab-3(mw105) gonad arm with multiple turns and ventralized DTC migration (D). Dorsal is up, ventral is down. Dashed line traces the gonad arm with arrow at DTC. Bars, 25 μm.