Figure 4.

Expression of the recombinant M. albomyces laccase gene lac1, the cellulase gene cbh1 and protein folding factor genes pdi1 and bip1 in batch and fed-batch cultures of T. reesei. A. lac1 mRNA level relative to biomass, specific extracellular production rate of laccase r_MaL, specific growth rate μ. B. cbh1 mRNA relative to biomass (batch and fed-batch) and relative to polyA RNA (fed-batch) and specific extracellular production rate of CBHI. C. pdi and bip1 mRNA relative to polyA RNA. Dotted, vertical lines in the fed-batch culture represent the start and end of lactose feed.