Figure 2.

Histology of GFAP labeled astrocytes (cortical layers 1–3): GFAP containing cells are represented by brown staining (arrows). These images are representative of the areas of the cortex that were graded for with quantitative scaling. The hydrocephalic animals have more astrocytes in comparison to the age-matched control animals. Shunting reduced the relative overall appearance of stained astrocytes, although not to control levels. Scale bars = 25 μm. The upper right corner shows low power images of control (upper), untreated hydrocephalic (center) and shunted animal (lower) at 36d. Shunting resulted in re-expansion of the cortex, and dramatically reduced the apparent ventricular volume.