TABLE III.
Allele Frequencies of ApoE C112R and R158C
ApoE112 |
ApoE158 |
||||||||
---|---|---|---|---|---|---|---|---|---|
Alleles | C | R (%) | OR (CI) | X2/P | R | C (%) |
C carrier OR (CI) |
X2/P | |
All controls | 454 | 373 | 81 (17.8) | 408 | 46 (10.1) | ||||
Controls | 266 | 216 | 50 (18.8) | 236 | 30 (11.3) | ||||
Blood donors | 188 | 157 | 31 (16.5) | 172 | 16 (8.5) | ||||
All AMD | 320 | 285 | 35 (10.9) | 0.53 (0.33–0.80) | 7.4/0.007 | 222 | 18 (7.5) | 0.89 (0.49–1.40) | 0.44/0.51 |
CD AMD | 240 | 209 | 31 (12.9) | 0.63 (0.43–1.05)a | 3.18/0.08a | 222 | 18 (7.5) | 0.82 (0.40–1.30)a | 1.03/0.31a |
0.68 (0.44–1.19)b | 1.69/0.19b | 1.01 (0.51–1.03)b | 0.01/0.94b | ||||||
PD AMD | 80 | 76 | 4 (5) | 0.23 (0.09–0.69)a | 8.24/0.004 |
In comparison with screened controls.
In comparison with blood donor controls.