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Detection of DNA (arrows) of Bovine herpesvirus 4 (BoHV-4) by in situ hybridization in 3 aborted bovine fetuses: a) in renal tubular epithelial cells of fetus 4; (b) in splenic lymphocytes and monocytes of fetus 3, and (c) in hepatic Kupffer cells of fetus 3. Note the depletion, karyorrhexis, and karyopyknosis of the splenic lymphocytes and the karyorrhexis of the hepatocytes.
