Table II.

Nucleotide similarity of a 222-base-pair fragment of open reading frame 2 of the HEV genome of swine and human strains of genotype 3, as compared with 6 strains isolated in this study

	Study strains (GenBank accession no. of the sequence); % similarity of fragment
Selected strainsa	SpswfCV3 (DQ093564)	SpswsCV4 (DQ093565)	SpswfCV5 (DQ093566)	SpswmCV6 (DQ093567)	SpswmCV7 (DQ093568)	SpswsCV8 (DQ093569)
AF082843 US-SW	85.5	87.3	86.9	84.6	83.7	87.3
AF060668 US1	84.6	85.5	86.0	83.7	83.3	85.5
AF060669 US2b	85.5	85.5	86.0	83.7	85.1	85.5
AF336292 NLSW28	90.5	90.9	90.5	88.7	86.4	90.9
AF503511 UK P354	86.9	85.1	85.5	86.4	85.5	85.1
AF503512 UK P143	85.5	83.7	84.2	84.6	86.9	83.7
DQ093564 SpswfCV3	—	96.8	97.2	96.3	90.0	96.8
DQ093565 SpswsCV4	96.8	—	99.5	95.0	89.6	100
DQ093566 SpswfCV5	97.2	99.5	—	95.4	90.0	99.5
DQ093567 SpswmCV6	96.3	95.0	95.4	—	89.1	95.0
DQ093568 SpswmCV7	90.0	89.6	90.0	89.1	—	89.6
DQ093569 SpswsCV8	96.8	100	99.5	95.0	89.6	—
AF195063 E11	97.2	98.6	98.1	94.5	89.1	98.6
AF195062 VH2	93.6	94.1	93.6	91.8	91.4	94.1
AF195061 VH1	92.7	92.3	91.8	90.0	89.1	92.3
AY858936 G3-8f	83.3	85.1	85.5	83.3	84.2	85.1
AY858920 S2-29f	86.9	87.8	87.3	85.1	84.6	87.8
AY858917 S1-29f	86.0	86.9	86.4	86.0	84.2	86.9
AY858901 T4-7s	83.7	83.7	83.3	81.9	82.4	83.7
AF516179 KOR2	86.0	86.9	87.3	86.0	85.5	86.9
AY115488 CANADA	85.1	85.1	85.5	86.0	83.7	85.1
AB073910 swJ681	81.9	82.8	83.3	82.8	81.5	82.8

^aThose in italics are of swine origin and those underlined are of human origin.

^bFor this strain, the deduced amino acid sequence of the fragment was 99% identical to that of all 6 of this study’s strains, whereas for all of the other selected strains the similarity was 100%.