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. Author manuscript; available in PMC: 2008 Apr 1.
Published in final edited form as: Neurobiol Dis. 2007 Jan 23;26(1):56–65. doi: 10.1016/j.nbd.2006.11.013

Figure 2.

Figure 2

Spontaneous locomotor activity progressively decreases with advancing age. Data represents total distance traveled (cm) in a video recording cage over a thirty minute interval prior to MPTP treatment (Pre) and 3 months after induction of unilateral parkinsonism (Post). Prior to MPTP treatment, spontaneous activity was noted to decrease progressively with advancing age, reaching statistical significance for the comparison of young adult animals to aged animals (* p=0.005). Further decreases in motor activity were noted after MPTP treatment, but these were not statistically different between age groups.