FIG. 4.

Model to explain the generation of inverted dicentric dimers and their subsequent processing into translocations. The designations AB and A'B' indicate the orientations of Ty elements; the A' strand is complementary to A and the B' strand is complementary to B. In this diagram, we depict the formation of only one type of chromosome aberration, a translocation. Other types of aberrations can be generated by similar mechanisms, as discussed in the text. Ty1α and Ty1β, blue and purple arrows.