FIG. 2.

Deletion of KU70 reversed the increased sensitivity of rad18-deficient cells to γ-irradiation and CPT. (A and B) Fractions of colonies surviving after γ-irradiation compared with untreated controls. The data are shown as in Fig. 1A. (C) Deficient DSB repair during the G₂ phase in rad18 cells was restored by inactivation of Ku70. The data are shown as in Fig. 1C. (D) Fractions of colonies surviving after continuous exposure to CPT. The data are shown as in Fig. 1D. WT, wild type.