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RRM1 is required for nuclear export of hLaΔΝRE. IF of S. pombe cells transformed with various hLa NRE-defective constructs that lack the LM (hLaΔΝRE-ΔLM) (A), RRM1 (hLaΔΝRE-ΔRRM1) (B), RRM2 (hLaΔΝRE-ΔRRM2) (C), or RRM1 in the context of K316A/K317A (hLaK316A/K317A-ΔRRM1) (D) is shown.
