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Time-lapse microscopic analysis of Cdc20 and securin mutant embryos. Cdc20gt/gt (A) and Cdc20gt/gt securin−/− (B) E1.5 embryos were cultured in KOSM for 8 to 9 h before the addition of Hoechst 3344 dye to the medium. Time zero was set at 30 min after the Hoechst dye addition. Scale bars, 10 μm.
