TABLE 1.
Rescue of the lethality of homozygous mrn alleles by different transgenic flies
| Mutant genotype | Lethality rescue by transgenic fly (%)a:
|
||||
|---|---|---|---|---|---|
| Dmp52-1 | Dmp52-1/Dmp52-2 | Dmp52-mutb | hp52-2 | hp52-1/hp52-3 | |
| mrn1/mrn1 | 2.4 (540) | 3.4 (256) | 0 (200) | 0 (262) | 2 (111) |
| mrn3/mrn3 | 5.0 (592) | 6.0 (168) | 0 (190) | 1.5 (126) | 3.5 (109) |
| mrn5/mrn5 | 10.4 (281) | 15.0 (267) | NA | NA | 7.8 (153) |
a
The percentage represents recovery of homozygous flies compared to the expectation for full complementation (number in parentheses). NA, not analyzed.
b
The Dmp52-mut line is a transgenic line expressing the double point mutant (E340K-R34YE).