FIG. 1.

Gene structure, schematic representation, deduced amino acid sequences, and expression of BSX1A and BSX1B. (A) Both BSX1A and BSX1B are encoded by three coding exons (squares) on mouse chromosome 9. The horizontal lines indicate noncoding genomic DNA. HD, homeodomain (black squares); N, N-terminal region; C, C-terminal region. The BSX1B-specific region is shaded. (B) Deduced amino acid sequences of BSX1A and BSX1B. The homeodomain sequence is underlined. (C) Immunohistochemistry on neonatal mouse hypothalamic sections using anti-BSX1A and anti-BSX1B sera. On the right are high-magnification images. Immunoreactive cells were detected around the third ventricle (arrows). III, third ventricle; ME, median eminence; NC, negative control.