TABLE 3.
The sy262 mutation is strongly dependent on upstream signaling by EGF
| Genotypea | Gonadb | Vulval Inductionc | % Muvd | % Vule | nf | P valueg |
|---|---|---|---|---|---|---|
| Wild type | + | 3.00 | 0 | 0 | 24 | |
| Wild type | − | 0.00 | 0 | 100 | 14 | |
| let-23(rf); sy262 | + | 3.80 | 68 | 0 | 22 | |
| let-23(rf); sy262 | − | 0.00 | 0 | 100 | 19 | |
| let-23(rf); let-60(gf)/+ | + | 4.58 | 100 | 0 | 20 | |
| let-23(rf); let-60(gf) | + | 5.38 | 100 | 0 | 20 | |
| let-23(rf); let-60(gf) | − | 1.17 | 12 | 88 | 16 | 0.01 to wild type gonad ablated |
a
let-23(rf) = let-23(sy1), let-60(gf) = let-60(n1046gf), and sy262 was linked to him-5(e1490).
b
The gonadal primordium, which gives rise to the EGF-producing anchor cell, is either present (+) or removed by laser ablation (−).
c
Average number of vulval progenitor cells adopting vulval fates. Wild type is three. The maximum is six.
d
The percentage of animals that have more than three vulval progenitor cells adopting vulval fates.
e
The percentage of animals that have fewer than three vulval progenitor cells adopting vulval fates.
f
n, number of animals examined.
g
Statistical significance of the vulval induction value as determined by a two-tailed Student's t test.