FIG. 2.
Aberrant expression of ExPa genes in the colons of Dnmt1c/+ mice. (A) Bisulfite genomic sequencing of the mouse Tff2 promoter region in the colon of wild-type and Dnmt1c/+ C57BL/6 mice. CpGs are represented by vertical lines. Brackets show PCR products amplified after bisulfite treatment. Empty circles represent unmethylated cytosine residues, and filled circles represent methylated cytosine residues. (B) Real-time RT-PCR analysis of ExPa gene expression in wild-type and Dnmt1c/+ C57BL/6 mouse colons. Each horizontal row corresponds to one mouse. Values correspond to the fold overexpression of genes normalized to average expression in wild-type samples.