pYStat3 and ITGαvβ6 expression in prostate cancer cells. An association between tumor characteristics, ITGαvβ6 immunostaining, and pYStat3 immunostaining is displayed in the table. Microtissue arrays were stained with anti-phospho-Stat3 and anti-ITGαvβ6 antibodies. Examples of relative pYStat3 and ITGαvβ6 staining patterns are indicated by the large arrowheads showing cancer cells and the small arrowheads showing nontumorous basal cells. The number associated with each section corresponds to the Imgenex tissue microarray designation. Scores for pYStat3 staining patterns are as follows: tumor 13, +3; tumor 31, +1; tumor 11, 0; tumor 30, +2; tumor 17, +1; and benign tissue 44, +2. Scores for ITGαvβ6 staining patterns are as follows: tumor 13, +1; tumor 31, 0, tumor 11, +3; tumor 30, 0; tumor 17, 0; and benign tissue 44, +3. PSA, prostate-specific antigen.