. 2007 Apr 16;27(12):4454–4464. doi: 10.1128/MCB.00133-07

TABLE 1.

Breeding results from nkd1^lacZ and nkd2^lacZ crosses^a

Background and cross	No. of pairs	No. of litters	No. of pups/litter	No. of mice of each genotype
Background and cross	No. of pairs	No. of litters	No. of pups/litter	+/+	+/−	−/−
Bl6-129 hybrid
nkd1^lacZ/+ × nkd1^lacZ/+	9	15	7.3	32	55	23
nkd2^lacZ/+ × nkd2^lacZ/+	5	14	7.4	25	52	26
129
nkd1^lacZ/+ × nkd1^lacZ/+	10	23	4.9	29	50	27
nkd2^lacZ/+ × nkd2^lacZ/+	3	4	5.8	9	7	7
Total (both)
nkd1^lacZ/+ × nkd1^lacZ/+				61	105	50
nkd2^lacZ/+ × nkd2^lacZ/+				34	59	33
Bl6-129 hybrid
nkd1^lacZ/lacZ × nkd1^lacZ/lacZ	6	19	5.3
nkd2^lacZ/lacZ × nkd2^lacZ/lacZ	9	33	6.4
129
nkd1^lacZ/lacZ × nkd1^lacZ/lacZb	6	1	1
nkd2^lacZ/lacZ × nkd2^lacZ/lacZ	6	20	4.5

For each cross, the number of breeding pairs, the number of litters, and the mean number of pups per litter are indicated.

^bAmong six breeding pairs, a single litter consisting of a single pup was produced during a 3-month period. No histologic abnormalities were noted in the testes or ovaries of nkd1^lacZ/lacZ animals in the 129 background, although one of the males had unilateral testicular agenesis.