FIG. 3.

Predicted effects of mutations on the structure of the 69-nt MHV PS. Structure of the wild-type 69-nt MHV PS (A) adapted from the work of Fosmire et al. (3) and (B) redrawn to the new model. The boxed residues indicate the sequences of the FB series mutants FB7, FB8, FB12, and FB13, which were constructed by Fosmire et al. (3), where Δ stands for deletion. The two extra residues (g and c) at the 5′ end were vector derived and stabilized the structure shown in panel B.