TABLE 3.
Temporal deposition of PrPd in extraneural structures after e.n. inoculation
Structure | No. of PrPd-positive hamsters/total no. of e.n.-inoculated hamsters at time point (in wk) postinoculation:
|
||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|
2 | 4 | 6 | 8 | 10 | 12 | 14 | 16 | 18 | 20 | 22 | |
Nasal cavity: NALT | 0/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | ND | ND | 3/3 |
Submandibular lymph node | 0/3 | 1/3 | 2/3 | 3/3 | 3/3 | 3/3 | 3/3 | 3/3 | ND | ND | 3/3 |
Cervical lymph node | ND | ND | 0/3 | 1/3 | 3/3 | 2/2 | 3/3 | 3/3 | ND | ND | 3/3 |
Mesenteric lymph node | ND | ND | ND | ND | ND | 0/3 | 2/3 | 1/3 | 1/3 | 3/3 | 3/3 |
Spleen | ND | ND | ND | ND | 0/3 | 0/3 | 2/3 | 3/3 | ND | ND | 3/3 |
Peyer's patch | ND | ND | ND | ND | ND | 0/3 | 1/3 | 1/3 | 2/3 | 3/3 | 3/3 |
Tongue | ND | ND | ND | ND | ND | ND | ND | ND | 0/3 | 1/3 | 2/3 |