FIG. 3.

Magnitude of neutralizing antibody responses against a panel of heterologous HIV pseudoviruses among patients with asymptomatic HIV-1 (n = 32) or HIV-2 (n = 35) infection. (A) Comparison of the magnitude of neutralizing antibody responses against HIV reporter viruses. The magnitude of the responses was defined based on the median IC₅₀ titer against all primary heterologous viruses, where a response was positive for neutralization. For HIV-1-infected subjects, the magnitude of neutralizing response against heterologous viruses was significantly higher than that for HIV-2-infected subjects (P = 0.035). (B) Relationship between magnitude of neutralizing antibody response and viral load for HIV-1-infected (triangles) or HIV-2-infected (circles) subjects. There was a significant positive correlation between viremia and the magnitude of the neutralizing response for HIV-1-infected (r = 0.63; P = 0.011) and HIV-2-infected (r = 0.59; P = 0.017) groups.