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. 2007 Mar 7;81(10):5112–5120. doi: 10.1128/JVI.02197-06

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FIG. 4. — HCMV apparently inhibits transcription of the genes encoding PDGFR-α and -β in SMCs. PDGFR-α and PDGFR-β mRNA levels were determined by analysis of total cellular mRNA by real-time PCR, and the data are presented as means ± standard errors of the means in arbitrary units (n = 6 to 12). (A and B) Dose-dependent effects of HCMV (AD169; MOI, 0.1 to 10) infection for PDGFR-α mRNA (A) and PDGFR-β mRNA (B) levels (n = 6). (C and D) Time dependency of the effects of infection with this same strain of HCMV for the level of PDGFR-α mRNA (C) and PDGFR-β mRNA (D) in uninfected or infected HPASMC. (E) Time dependency of the effects of HCASMC infected by the endothelial cell-adapted clinical isolate VR1814 on PDGFR-β mRNA levels.