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. 2007 Mar 7;81(10):5112–5120. doi: 10.1128/JVI.02197-06

FIG. 5.

FIG. 5.

Downregulation of PDGFR expression in HCMV (AD169)-infected SMCs is dependent on the expression of IE and/or E viral genes. (A and B) Expression of PDGFR-α (A) and -β (B) following infection of SMCs with HCMV, HCMV inactivated by UV irradiation (UV-HCMV), infection of SMCs pretreated with IVIG (IVIG-HCMV), and virus-cleared supernatants (filtered HCMV) and in HCMV-infected SMCs treated with the anti-HCMV drug foscarnet as determined by flow cytometric analysis at 3 dpi. The values presented are mean channel values ± standard errors of the means (n = 7 to 10). (C and D) Expression of PDGFR-α (C) and -β (D) following infection of SMCs by virus-cleared supernatants collected at 4 h, 12 h, 24 h, and 72 h as determined by flow cytometric analysis at 3 dpi. Values presented are mean channel values ± standard errors of the means (n = 3).