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Th1- and Th2-regulated genes induced in the lung during primary RSV infection
| Category | No. of genes regulated by:
|
|
|---|---|---|
| Th1a | Th2b | |
| Chemoattraction | 4 | |
| IFN response | 11 | |
| Antigen processing | 9 | |
| Inflammation | 1 | 5 |
| Metabolism | ||
| Total | 25 | 5 |
Th1 genes are genes regulated by IFN-γ or involved in IFN-γ-mediated responses.
Th2 genes are genes that have been associated with Th2 responses or that were shown to be up-regulated in two models for allergic asthma (22).
