TABLE 2.
Distribution and estimates of viral loads in tissues of SIV-infected rhesus macaques
| Tissuea | RPb
|
CPb
|
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 147 | 168 | 538 | 567 | 445 | 426 | 18655 | 119 | 120 | 133 | 187 | 063 | 454 | 460 | |
| Lymphoid | ||||||||||||||
| Thymus | 2 | 4 | 3 | 1 | 3 | 2 | 2 | 1 | 0 | 0 | 0 | 1 | 1 | 1 |
| ALN | 2 | 2 | 4 | 4 | 4 | 2 | 3 | 1 | 1 | 1 | 2 | 1 | 1 | 1 |
| ILN | 3 | 3 | 4 | 4 | 3 | 2 | 4 | 1 | 1 | 1 | 2 | 1 | 1 | 1 |
| TBLN | 3 | 4 | 2 | 2 | 4 | 3 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 |
| MLN | 4 | 4 | 4 | 4 | 4 | 2 | 4 | 1 | 1 | 1 | 2 | 2 | 2 | 1 |
| Spleen | 3 | 2 | 4 | 4 | 4 | 1 | 4 | 1 | 1 | 1 | 2 | 1 | 1 | 1 |
| Ileum | 3 | 3 | 4 | 4 | 4 | 3 | 4 | 1 | 0 | 1 | 1 | 1 | 1 | 2 |
| Colon | 3 | 3 | 3 | 4 | 4 | 2 | 4 | 1 | 1 | 1 | 1 | 1 | 1 | 0 |
| Nonlymphoid | ||||||||||||||
| Lung | 4 | 4 | 4 | 3 | 4 | 3 | 4 | 0 | 0 | 0 | 0 | 1 | 1 | 1 |
| Liver | 1 | 1 | 4 | 2 | 3 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Kidney | 3 | 2 | 2 | 3 | 3 | 2 | 3 | 0 | 0 | 0 | 0 | 1 | 0 | 0 |
| Heart | 2 | 3 | 2 | 2 | 2 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Brain | 2 | 3 | 4 | 4 | 3 | 3 | 4 | 1c | 0 | 0 | 0 | 0 | 0 | 1 |
| Spinal cord | 2 | 3 | 2 | 1 | ND | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Eye | 2 | 2 | 3 | 3 | 3 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Uterus | NA | NA | 4 | 3 | NA | NA | NA | NA | NA | NA | NA | 1 | 0 | 0 |
| Ovary | NA | NA | 4 | ND | NA | NA | NA | NA | NA | NA | NA | 0 | 0 | 0 |
| Prostate | 3 | 3 | NA | NA | 3 | 0 | 2 | 0 | 0 | 0 | 0 | NA | NA | NA |
| Testis | 3 | 3 | NA | NA | 2 | 1 | 3 | 0 | 0 | 0 | 1 | NA | NA | NA |
a
ALN, axillary lymph node; ILN, inguinal lymph node; TBLN, tracheobronchial lymph node; MLN, mesenteric lymph node.
b
0, no SIV+ cells observed in entire section; 1, rare SIV+ cell per high-power field; 2, 1 to 5 SIV+ cells per high-power field; 3, 5 to 10 SIV+ cells per high-power field; 4, >10 SIV+ cells per high-power field; ND, not determined; NA, not applicable.
c
One focal area or a single positive cell was observed.