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. 2007 Mar 28;81(11):5850–5863. doi: 10.1128/JVI.02403-06

FIG. 1.

FIG. 1.

Sequence variation in the domain IIIe structures of hepacivirus, pestivirus, and picornavirus HP-like IRESs. (A) Alignment of sequences corresponding to domain IIIe and flanking nucleotides (for accession numbers, see Materials and Methods). (B to E) Structurally neutral substitutions in isolates of AEV (B and D) and PTV (C and E), shown as aligned sequences (B and C) and mapped onto partial secondary structure models (D and E) of AEV (Calnek) (D) and PTV-1 IRES domain IIIe (E). PTV-2 (DS 756) refers to PTV-2 (DS 756/93). PTV-10 (UKG) refers to PTV-10 (UKG 170/80). (A to C) The 5′ and 3′ borders of each element are numbered; identical nucleotides are shaded.