TABLE 4.
Cumulative papilloma volumes in rabbits treated with VSV-based CRPV vaccine(s)
| CRPV dilution and vaccine component | Result obtained by administration of following vaccine component:
|
||||
|---|---|---|---|---|---|
| VSV-E1 | VSV-E2 | VSV-E6 | VSV-E7 | None | |
| 1:30 | |||||
| VSV-E1 | 6,271 ± 1,298a | 7,926 ± 1,258 | 4,683 ± 670 | 3,990 ± 370 | |
| VSV-E2 | 2,937 ± 751 | 3,857 ± 1,762 | 4,250 ± 1,205 | ||
| VSV-E6 | 6,414 ± 331 | 4,346 ± 1,184 | |||
| VSV-E7 | 553 ± 285 | ||||
| VSV-rwt | 13,355 ± 2,241 | ||||
| Medium | 9,084 ± 879 | ||||
| 1:150 | |||||
| VSV-E1 | 1,853 ± 339 | 4,236 ± 702 | 2,096 ± 325 | 2,433 ± 422 | |
| VSV-E2 | 1,223 ± 340 | 1,804 ± 865 | 2005 ± 646 | ||
| VSV-E6 | 3,458 ± 570 | 1,629 ± 671 | |||
| VSV-E7 | 49 ± 21 | ||||
| VSV-rwt | 7,288 ± 1,660 | ||||
| Medium | 4,828 ± 470 | ||||
| 1:750 | |||||
| VSV-E1 | 1,099 ± 364 | 1,540 ± 411 | 1,187 ± 271 | 824 ± 234 | |
| VSV-E2 | 406 ± 235 | 655 ± 333 | 549 ± 178 | ||
| VSV-E6 | 1,045 ± 153 | 533 ± 231 | |||
| VSV-E7 | 1.6 ± 1.0 | ||||
| VSV-rwt | 2,732 ± 979 | ||||
| Medium | 2,106 ± 539 | ||||
a
Volume, in cubic millimeters (mean ± SEM). Values are descriptive; they were not used to calculate statistical significance.