TABLE 5.
Analysis of treatment effects on cumulative papilloma volumes
| Effect and vaccine(s) | ATSa | P value |
|---|---|---|
| Vaccinationb | ||
| VSV-E1 | 3.97 | 0.0462 |
| VSV-E2 | 7.35 | 0.0067 |
| VSV-E6 | 5.29 | 0.0215 |
| VSV-E7 | 80.3 | <0.0001 |
| Interactionc | ||
| VSV-E1-VSV-E2 | 7.84 | 0.0051 |
| VSV-E1-VSV-E6 | 0.78 | 0.38d |
| VSV-E1-VSV-E7 | 22.32 | <0.0001 |
| VSV-E2-VSV-E6 | 0.24 | 0.63d |
| VSV-E2-VSV-E7 | 12.41 | 0.0004 |
| VSV-E6-VSV-E7 | 7.41 | 0.0065 |
a
ATS, ANOVA-type statistic.
b
The effects of each vaccine were analyzed by considering its contributions to the four groups receiving it (Table 1) while taking into account the effects of the other vaccines and their corresponding pairing effects.
c
The effects of each pair of vaccines were analyzed by considering the pair's effects in the three rabbits receiving it (Table 1) after taking away the effects of the vaccines in the pair.
d
No statistically significant difference.