Fig. 2.

PTN secretion from MCF-7-Ptn cells stimulates s.c. xenograft growth in vivo. (A) MCF-7-mock cell, MCF-7-Ptn cell, and MCF-7-Ptn/NIH 3T3 cell xenograft growth in flanks of nude mice. Day 1 is the time of detection of the first palpable xenograft. (B) Histological phenotype of sections of MCF-7-mock cell xenografts (H&E). (C) Histological phenotype of sections of MCF-7-Ptn cell xenografts (H&E). (D) Histological phenotype of sections of MCF-7-Ptn Xenografts (Masson trichrome). (Scale bar: 100 μm.)