Skip to main content
. 2007 May 3;35(10):3431–3441. doi: 10.1093/nar/gkm214

Figure 2.

Figure 2.

Spatial and temporal patterns of the induction of histone acetylation at the HLA-DRA gene. (A) The levels of H4 (top, H4Ac) and H3 (bottom, H3Ac) acetylation were measured by quantitative ChIP at different positions within the HLA-DRA gene in non-induced cells and cells treated with IFN-γ for 12 h. A schematic map of the HLA-DRA gene is shown below. (B) The levels of H4 (left) and H3 (right) acetylation were measured by quantitative ChIP at the indicated positions after induction with IFN-γ for the indicated times. For H4Ac, similar time courses were also observed at the other positions examined in (A) (data not shown). Asterisk denotes not measured in all experiments. All results are expressed relative to the value observed at the promoter in non-induced cells. The mean and SD are shown for four (H4Ac) and five (H3Ac) experiments.