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. 2007 Apr 25;35(10):3297–3305. doi: 10.1093/nar/gkm205

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© 2007 The Author(s)

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Sequence alignment of four RNA(m⁵U)methyltransferases with known biochemical function. The conserved motifs, TRAM domain and amino acid substitutions (asterisk, number and nature of the amino acid) investigated in this work are marked. The translational start of the Trm2p is according to (4).