Figure 5.
Interactions between amino acid chains, the target uridine and SAH in the active site of RumA. Several selected amino acids in the active site are divided into (A) and (B) for better representation. Corresponding residues in the TrmA are shown within the parenthesis. The image was created with the SwissPDB Viewer program (40) http://www.expasy.org/spdbv/) using the coordinates of RumA-RNA-SAH complex (2BH2) (11) from the Protein Data Bank (http://www.rcsb.org/pdb/home/home.do). Putative hydrogen bonds are represented by dashed lines.