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(A) Gross cardiac anatomy of adult WT (+/+) and CASQ307/307 mice (n = 4) demonstrated enlarged atria (arrows) and ventricles in mutant hearts. (B) Low magnification of paraffin-embedded ventricular transverse heart sections from 35-week-old mice studied with Masson trichrome stain. No fibrosis was observed in either WT (+/+) or homozygous CASQ307/307 mice (n = 4). (B). Scale bars, 1 mm.
