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. 2007 Jul 2;117(7):1988–1994. doi: 10.1172/JCI31097

Figure 3. Effect of antimicrobial peptides on growth of Mycobacterium tuberculosis in microbiological broth media.

Figure 3

(A) Effect of lipocalin 2 on growth of MTB in iron-replete and iron-depleted broth. Effect of lipocalin 2 (5 μg/ml) on growth of an inoculum of 3 × 104 CFU/ml MTB was determined in iron-replete (150 μM Fe) and iron-depleted (10 nM Fe) 7H9 broth medium. The mean of 6 replicates is shown. Error bars represent SEM. (B) Effect of cathelicidin LL-37 on the growth of MTB in broth. Effect of cathelicidin LL-37 (0.1–100 μg/ml) on growth of an inoculum of 6 × 105 CFU/ml MTB was determined in iron-depleted (10 nM Fe) 7H9 broth medium. The mean of 4 replicates is shown. Error bars represent SEM. (C) Effect of HNP1–3 on the growth of MTB in broth. Effect of HNP1–3 (0.1–100 μg/ml) on growth of an inoculum of 6 × 105 CFU/ml MTB was determined in iron-depleted (10 nM Fe) 7H9 broth medium. The mean of 4 replicates is shown. Error bars represent SEM.