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. Author manuscript; available in PMC: 2007 Jun 29.
Published in final edited form as: Bioorg Med Chem Lett. 2006 Sep 1;16(22):5773–5777. doi: 10.1016/j.bmcl.2006.08.078

Figure 1.

Figure 1

Relative inhibition of the 192-member urea library at 100 nM concentration compared to the corresponding adamantane-based ureas 1{1}, 2{1}, 3{1}, and 4{1}, respectively. Black square: equal to or greater than 80% of inhibition obtained when R1 is an adamantyl group; grey square: less than 80% of the inhibition obtained when R1 is an adamantyl group; white square: compounds were not tested due to the poor purity (less than 90%).