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. 2007 Jun 11;8:32. doi: 10.1186/1471-2350-8-32

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Copyright © 2007 Vasickova et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Multiplex ligation-dependent probe amplification (MLPA) electropherogram (ABI PRISM 310 genetic analyzer, Applied Biosystems). Probe mix P002 contains 34 probes: nine control probes recognizing non-BRCA1 sequences on various chromosomes are indicated by "c"; exons recognized by the BRCA1-specific probes are indicated by numbers (probes for both alternative exons 1...1A, 1B; exon 4 is not present in normal BRCA1 transcript; two probes specific for exon 11 are included). Note decreased peak heights of deleted exons.