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. 2007 Jul 6;3(7):e112. doi: 10.1371/journal.pgen.0030112

Figure 4. CTCF Binding Sites Demarcate Boundaries in the BX-C.

Figure 4

The top track shows the BX-C cis-regulatory regions above a coordinate line with numbering according to Martin et al. [20]. The coloured bar indicates the regulatory domains according to Maeda and Karch [28]. The orange/yellow regions (abx/bx and bxd/pbx) control Ubx expression. The blue shaded regions (iab-2, 3, and 4) control abd-A expression, and the green regions (iab-5 to 9) regulate Abd-B. Above the Drosophila genome Release 4 coordinate line, are shown the insertion points and associated regulation of a set of enhancer-trap insertions [27]. The locations of CTCF sites are indicated by red vertical bars. The positions of the CTCF sites correlate well with the boundaries of the cis-regulatory regions and separate sets of enhancer-traps with different regulation.