Table 3.
Surface MHC-II levels in neonatal and adult monocytes
| Adult Monocytes HLA-DR1 | MHC-II (MCF)** | Neonatal Monocytes HLA-DR1 | MHC-II (MCF)** |
|---|---|---|---|
| AM1 | 132 | NM24 | 151 |
| AM14 | 79 | NM25 | 76 |
| AM19 | 194 | NM32 | 37 |
| AM21 | 94 | NM39 | 80 |
| AM22 | 140 | NM80 | 92 |
| AM23* | 126 | NM81 | 176 |
| AM24 | 135 | NM93 | 132 |
| AM34 | 148 | NM97 | 58 |
| Average | 131 | Average | 100 |
| % Difference P value | 24% ↓ 0.189 | ||
| HLA-DR3 | HLA-DR3 | ||
| AM2 | 278 | NM33 | 56 |
| AM23* | 126 | NM50 | 71 |
| AM54 | 50 | NM52 | 97 |
| AM58 | 156 | NM56 | 131 |
| AM62 | 192 | NM60 | 49 |
| AMG7 | 135 | NM83 | 66 |
| AM70 | 96 | NM90 | 34 |
| Average | 148 | Average | 72 |
| % Difference P value | 51 % ↓ 0.035 | ||
| All adult monocytes (HLA-DR1 + HLA-DR3) | All neonatal monocytes (HLA-DR1 + HLA-DR3) | ||
| Average | 140 | Average | 87 |
| % Difference P value | 37.9% ↓ 0.003 |
*
AM23 expresses both HLA-DR1 and HLA-DR3
**
MCF = Mean Channel Fluorescence