TABLE 1.
Non-EX
|
EX
|
|||
---|---|---|---|---|
Parameters | aCSF | Ang II | aCSF | Ang II |
Body weight, g | 408 ± 9 | 397 ± 5 | 381 ± 6 | 376 ± 6 |
Left ventricle, g | 0.85 ± 0.03 | 0.77 ± 0.04 | 0.81 ± 0.06 | 0.9 ± 0.05 |
LV/BW, mg/g | 2.1 ± 0.1 | 1.9 ± 0.1 | 2.3 ± 0.1 | 2.4 ± 0.1 |
Basal MAP, mm Hg | 88.7 ± 5.3 | 95.7 ± 3.8 | 86.1 ± 4.2 | 89.4 ± 5.1 |
Basal HR, bpm | 375 ± 13 | 392 ± 10 | 360 ± 14 | 370 ± 9 |
Basal RSNA, % of maximum | 40.6 ± 5.3 | 67.4 ± 4.7* | 37.9 ± 4.3 | 46.2 ± 6.0† |
Water intake, mL/kg per day | 45.7 ± 3.4 | 61.8 ± 3.5* | 48.5 ± 4.1 | 62.2 ± 3.0* |
CS, μmol/min per gram | 14.4 ± 3.0 | 15.0 ± 1.5 | 21.3 ± 1.3* | 24.3 ± 2.2* |
Values are mean ± SE. n = 14 in each group. LV indicates left ventricle; BW, body weight; CS, citrate synthase activity.
P < 0.05 vs non-EX aCSF-infused rats;
P < 0.05 vs non-EX Ang II–infused rats.