TABLE 2.

Effects of Losartan (icv) on Arterial Baroreflex Function in Ang II–Infused Rats With or Without EX

Group	Range, % of Maximum	BP₅₀, mm Hg	Minimum RSNA, % of Maximum	Gain_max, % of Maximum/mm Hg
Non-EX Ang II infusion
Control	90.4 ± 4.6	88.4 ± 6.1	17.3 ± 1.7	1.6 ± 0.1
Losartan	102.7 ± 5.0	90.5 ± 6.0	8.9 ± 1.2^*	3.3 ± 0.1^*
EX Ang II infusion
Control	98 ± 5.6	89.1 ± 5.4	7.1 ± 0.8^†	3.2 ± 0.1^†
Losartan	103.4 ± 5.1	89.6 ± 3.8	6.2 ± 0.6^†	3.4 ± 0.1^†

Values are mean ± SE. n = 8 for each group. BP₅₀ indicates pressure at the midrange of the curve.

P < 0.05 losartan vs control;

^†

P < 0.05 vs control in non-EX rats.