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. Author manuscript; available in PMC: 2008 Jan 2.
Published in final edited form as: Mol Cell Endocrinol. 2006 Oct 11;260-262:65–72. doi: 10.1016/j.mce.2005.11.046

Table II.

cAMP responsiveness of cells expressing FLAG-LHR-wt and FLAG-LHR-D578H1

Cell Line Treatment Fold Increase over basal cAMP levels n
LHR-wt None 1.0a 9
LHR-wt 100 nM hCG 1.6 ± 0.1b 9
LHR-D578H None 2.1 ± 0.3b 9
LHR-D578H 1% MβCD 2.9 ± 0.6b 6
1

CHO cells expressing LHR-wt were assayed for cAMP expression following treatment with 100 nM hCG or following pretreatment of cells expressing LHR-D578H with MβCD. Results are expressed as the mean of the relative increase in cAMP ± S.E.M. compared to basal levels of cAMP in untreated CHO cells expressing LHR-wt receptors.

a

Means with different superscripts differ (p<0.03).

b

Means with different superscripts differ (p<0.03).