Fig. 1.
Synovial macrophages from rats with adjuvant arthritis were cultured for 24 h, and nitric oxide (NO) production analysed by measurement of nitrite in culture supernatants. Dexamethasone 10−7m (DEX) inhibited constitutive NO production (*P = 0·002). LPS 1 μg/ml induced NO production (**P = 0·001), and this induction was also inhibited by DEX (***P<0·001