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Schedule of experimental protocol for the induction of acute antigen-induced arthritis. Acute antigen-induced arthritis was induced in rabbits. Twenty-four hours before the intra-articular injection of ovalbumin (OVA) into the joint cavity, animals were randomly distributed into two groups: tenidap-treated (15 mg/kg per 12 h); and untreated. Animals were killed 24 h after the intra-articular injection. FCA, Freund's complete adjuvant.
