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Effect of pentoxifylline (PTX) therapy on in vitro ( a) TNF-α and (b) IL-10 release from (▪) peripheral blood mononuclear cells (PBMC) and (•) monocytes stimulated with Mycobacterium leprae. Data are mean ± s.e.m. of eight individual experiments. *Significant difference (P < 0.05) compared with levels obtained at the onset of the reactional episode (day 0).
