Fig. 1.

IL-10 production by monocytes and macrophages stimulated or not with lipopolysaccharide (LPS) and macrophage colony-stimulating factor (M-CSF). At given time points, macrophage cultures were washed, refed with fresh medium with or without LPS and M-CSF. After 48 h of incubation, the supernatants were obtained for IL-10 determination. The data represent the mean of three experiments each carried out in duplicate. Each experiment was performed with cells from a single donor. The error bars represent s.e.m.